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Protective immunity in hamsters from an oral Nipah vaccine correlates with pseudovirus neutralising antibody titre

Abstract Nipah virus (NiV) is a deadly zoonotic pathogen with a high mortality rate and no approved vaccines, creating an urgent need for new solutions. We developed a novel, thermostable, orally administered NiV vaccine using a human serotype 5 adenovirus (AdHu5) vector to express NiV glycoproteins...

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Principais autores: Meredith Stewart, Peter Bone, Andrew Bacon, Golnaz Emami, Lauren Cave, Elliot J. Bland, Stuart Dowall, Linda Easterbrook, Stephen Findlay-Wilson, Susan Fotheringham, Emma Kennedy, Ines Ruedas-Torres, Francisco J. Salguero, Craig Laferriere, Jeff Drew
格式: Artigo
語言:Inglês
出版: Nature Portfolio 2026-04-01
叢編:Scientific Reports
在線閱讀:https://doi.org/10.1038/s41598-026-40205-2
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