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Clostridium difficile Biofilm: Remodeling Metabolism and Cell Surface to Build a Sparse and Heterogeneously Aggregated Architecture

Clostridium difficile is an opportunistic entero-pathogen causing post-antibiotic and nosocomial diarrhea upon microbiota dysbiosis. Although biofilms could contribute to colonization, little is known about their development and physiology. Strain 630Δerm is able to form, in continuous-flow micro-fe...

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Principais autores: Isabelle Poquet, Laure Saujet, Alexis Canette, Marc Monot, Jovanna Mihajlovic, Jean-Marc Ghigo, Olga Soutourina, Romain Briandet, Isabelle Martin-Verstraete, Bruno Dupuy
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-09-01
Serier:Frontiers in Microbiology
Fag:
Clostridium difficile
biofilm formation
gene expression profiling
biofilm architecture
aggregates
Online adgang:https://www.frontiersin.org/article/10.3389/fmicb.2018.02084/full
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