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Original COVID-19 priming regimen impacts the immunogenicity of bivalent BA.1 and BA.5 boosters

Abstract Waning antibody responses after COVID-19 vaccination combined with the emergence of the SARS-CoV-2 Omicron lineage led to reduced vaccine effectiveness. As a countermeasure, bivalent mRNA-based booster vaccines encoding the ancestral spike protein in combination with that of Omicron BA.1 or...

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Asıl Yazarlar: Luca M. Zaeck, Ngoc H. Tan, Wim J. R. Rietdijk, Daryl Geers, Roos S. G. Sablerolles, Susanne Bogers, Laura L. A. van Dijk, Lennert Gommers, Leanne P. M. van Leeuwen, Sharona Rugebregt, Abraham Goorhuis, Douwe F. Postma, Leo G. Visser, Virgil A. S. H. Dalm, Melvin Lafeber, Neeltje A. Kootstra, Anke L. W. Huckriede, Bart L. Haagmans, Debbie van Baarle, Marion P. G. Koopmans, SWITCH-ON Research Group, P. Hugo M. van der Kuy, Corine H. GeurtsvanKessel, Rory D. de Vries
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Portfolio 2024-05-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-024-48414-x
Etiketler: Etiketle
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