NF-κB and IRF7 Pathway Activation by Epstein-Barr Virus Latent Membrane Protein 1
The principal Epstein-Barr virus (EBV) oncoprotein, Latent Membrane Protein 1 (LMP1), is expressed in most EBV-associated human malignancies. LMP1 mimics CD40 receptor signaling to provide infected cells with constitutive NF-κB, MAP kinase, IRF7, and PI3 kinase pathway stimulation. EBV-transformed B...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2013-06-01
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| Schriftenreihe: | Viruses |
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| Online-Zugang: | http://www.mdpi.com/1999-4915/5/6/1587 |
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