Microtubules depolymerization caused by the CK1 inhibitor IC261 may be not mediated by CK1 blockage.
The ubiquitously expressed serine/threonine specific casein kinase 1 (CK1) family plays important roles in the regulation of various physiological processes. Small-molecule inhibitors, such as the CK1δ/ε selectively inhibitor IC261, have been used to antagonize CK1 phosphorylation events in cells in...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2014-01-01
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| Serija: | PLoS ONE |
| Online dostop: | http://europepmc.org/articles/PMC4061085?pdf=render |
| Oznake: |
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