DNA Methyltransferase Inhibition Upregulates the Costimulatory Molecule ICAM-1 and the Immunogenic Phenotype of Melanoma Cells

In cutaneous melanoma, epigenetic dysregulation is implicated in drug resistance and tumor immune escape. However, the epigenetic mechanisms that influence immune escape remain poorly understood. To elucidate how epigenetic dysregulation alters the expression of surface proteins that may be involved...

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Main Authors:	Alessandra S.P. Cereghetti, Patrick Turko, Phil Cheng, Stephan Benke, Ala’a Al Hrout, Andreas Dzung, Reinhard Dummer, Michael O. Hottiger, Richard Chahwan, Lorenza P. Ferretti, Mitchell P. Levesque
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2025-03-01
Series:	JID Innovations
Subjects:	DNA methyltransferase DNMTi Epigenetics ICAM-1 Melanoma
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667026724000675
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