From Mice to Men: An Evolutionary Conserved Breakdown of the Epidermal Calcium Gradient and Its Impact on the Cornified Envelope

In previous publications, we could establish that a hallmark of human skin aging is the breakdown of the epidermal calcium gradient. This redistribution of calcium has many implications, including a restructuring of the cornified envelope, a reduced epidermal barrier function, a change in lipid comp...

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Autors principals:	Maria Karolin Streubel, Claudia Neuhofer, Johannes Bischof, Peter Steinbacher, Elisabeth Russe, Gottfried Wechselberger, Klaus Richter, Mark Rinnerthaler
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2018-06-01
Col·lecció:	Cosmetics
Matèries:	skin aging epidermal calcium gradient cornified envelope epidermal barrier loricrin filaggrin
Accés en línia:	http://www.mdpi.com/2079-9284/5/2/35
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