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Anti-inflammatory potential of aspergillus unguis SP51-EGY: TLR4-dependent effects & chemical diversity via Q-TOF LC-HRMS

Abstract Inflammation serves as an intricate defense mechanism for tissue repair. However, overactivation of TLR4-mediated inflammation by lipopolysaccharide (LPS) can lead to detrimental outcomes such as sepsis, acute lung injury, and chronic inflammation, often associated with cancer and autoimmun...

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Principais autores: Soad Nasr, Abdelhameed S. Dawood, Amal Mosad Ibrahim, Mohamed S. Abdel-Aziz, Walid Fayad, Anwar Abdelnaser, Faten K. Abd EL-Hady
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-09-01
Serier:BMC Biotechnology
Fag:
Aspergillus unguis SP51-EGY
TLR4
Anti-inflammatory
Macrophages
Q-TOF LC-HRMS
Online adgang:https://doi.org/10.1186/s12896-024-00890-1
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