Common pitfalls in drug target Mendelian randomization and how to avoid them
Abstract Background Drug target Mendelian randomization describes the use of genetic variants as instrumental variables for studying the effects of pharmacological agents. The paradigm can be used to inform on all aspects of drug development and has become increasingly popular over the last decade,...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2024-10-01
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| Serie: | BMC Medicine |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s12916-024-03700-9 |
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