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Spatial patterning of contractility by a self-organized mechanogen activity gradient underlies Drosophila gastrulation

Abstract During development cell deformations are spatially organized, however, how cellular mechanics is spatially controlled is unclear. Spatial control of cell identity often determines local cellular mechanics in a two-tiered mechanism. Theoretical studies also proposed that molecular gradients,...

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Bibliografische Detailangaben
Hauptverfasser: Gayatri Mundhe, Valentin Dunsing-Eichenauer, Jean-Marc Philippe, Élise Da Silva, Claudio Collinet, Thomas Lecuit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2026-01-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-026-68418-z
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