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Comparative analysis of DNA replication timing reveals conserved large-scale chromosomal architecture.

Recent evidence suggests that the timing of DNA replication is coordinated across megabase-scale domains in metazoan genomes, yet the importance of this aspect of genome organization is unclear. Here we show that replication timing is remarkably conserved between human and mouse, uncovering large re...

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Váldodahkkit: Eitan Yaffe, Shlomit Farkash-Amar, Andreas Polten, Zohar Yakhini, Amos Tanay, Itamar Simon
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2010-07-01
Ráidu:PLoS Genetics
Liŋkkat:http://europepmc.org/articles/PMC2895651?pdf=render
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