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The Toll for Trafficking: Toll-Like Receptor 7 Delivery to the Endosome

Toll-like receptor (TLR)-7 is an endosomal innate immune sensor capable of detecting single-stranded ribonucleic acid. TLR7-mediated induction of type I interferon and other inflammatory cytokine production is important in antiviral immune responses. Furthermore, altered TLR7 expression levels are i...

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Bibliografiske detaljer
Principais autores: Carlene Petes, Natalya Odoardi, Katrina Gee
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017-09-01
Serier:Frontiers in Immunology
Fag:
Online adgang:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01075/full
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