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Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.

Preventing parasite transmission from humans to mosquitoes is recognised to be critical for achieving elimination and eradication of malaria. Consequently developing new antimalarial drugs with transmission-blocking properties is a priority. Large screening campaigns have identified many new transmi...

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Hlavní autoři: Oleksiy Tsebriy, Andrii Khomiak, Celia Miguel-Blanco, Penny C Sparkes, Maurizio Gioli, Marco Santelli, Edgar Whitley, Francisco-Javier Gamo, Michael J Delves
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2023-10-01
Edice:PLoS Pathogens
On-line přístup:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011711&type=printable
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