Generation of two induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying MYBPC3 mutations

Hypertrophic cardiomyopathy (HCM) is a prevalent inherited cardiac disorder characterized by left ventricular hypertrophy and contractile dysfunction. Mutations in sarcomeric genes, particularly cardiac myosin-binding protein C (MYBPC3), are a leading cause of HCM. Here, we generated two induced plu...

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Principais autores:	Catherine A. Wu, Matthew A. Wu, Shane R. Zhao, Junyi Sun, Amira G. Flores-Banuelos, Parker Walther, Matthew Wheeler, Nazish Sayed
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2026-08-01
Series:	Stem Cell Research
Assuntos:	Hypertrophic cardiomyopathy (HCM) Induced pluripotent stem cells (iPSCs) Cardiac myosin-binding protein C (MYBPC3)
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S1873506126000784
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