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circ_0002456/FUS interaction inhibits NF-κB signaling to attenuate DNA damage and inflammatory responses in hDPSCs

Abstract Objectives circular RNAs (circRNAs) are emerging regulators of inflammatory diseases, but their role in pulpitis remains unclear. This study aimed to investigate the role of circRNA in the occurrence and development of pulpitis. Methods qRT-PCR and Western Blot were used to detect γ-H2AX, a...

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Hlavní autoři: Liecong Lin, Huixian Dong, Feng Lai, Jingkun Zhang, Bingtao Wang, Xiaohui Lv, Li Lin, Kehuan Hong, Yuxuan Zhao, Qianzhou Jiang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-06-01
Edice:Stem Cell Research & Therapy
Témata:
CircRNA
DNA damage
Pulpitis
FUS
NF-κB
On-line přístup:https://doi.org/10.1186/s13287-025-04391-6
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