Genomic and Phenotypic Characterization of the Nontoxigenic Clostridioides difficile Strain CCUG37785 and Demonstration of Its Therapeutic Potential for the Prevention of C. difficile Infection

ABSTRACT Symptoms of Clostridioides difficile infection (CDI) are attributed largely to two toxins, TcdA and TcdB. About 17–23% of C. difficile isolates produce binary toxin, which enhances C. difficile pathogenesis. Previously, we engineered the nontoxigenic C. difficile strain CCUG37785 (designate...

Ful tanımlama

Detaylı Bibliyografya

Asıl Yazarlar:	Shaohui Wang, Joshua Heuler, Ishani Wickramage, Xingmin Sun
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology 2022-04-01
Seri Bilgileri:	Microbiology Spectrum
Konular:	Clostridioides difficile infection (CDI) nontoxigenic Clostridioides difficile (NTCD) spores therapeutics microbial colonization pathogenicity locus
Online Erişim:	https://journals.asm.org/doi/10.1128/spectrum.01788-21
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!