Catastrophic disassembly of actin filaments via Mical-mediated oxidation
MICAL Redox enzymes post-translationally modify F-actin to promote its cellular destabilization. Here, the authors present a 3.9Å cryoEM structure of Mical-oxidized F-actin, showing its nucleotide-state dependent dynamic instability and susceptibility to cofilin-induced severing in the presence of i...
Salvato in:
| Autori principali: | , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2017-12-01
|
| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-017-02357-8 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|