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Alpha-1 Antitrypsin Deficiency Beyond COPD and Emphysema: A Narrative Review

<b>Background/Objectives</b>: Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder classically associated with emphysema and COPD. However, emerging evidence indicates that its clinical spectrum extends to airway-predominant diseases such as bronchiectasis and asthma, where protease–antiprote...

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Autori principali: Lucia Pastoressa, Vanessa Pivetti, Marialuisa Valente, Bianca Beghè, Enrico Clini, Roberto Tonelli, Stefania Cerri
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2026-02-01
Serie:Medical Sciences
Soggetti:
alpha-1 antitrypsin
chronic obstructive pulmonary disease
emphysema
asthma
bronchiectasis
neutrophil elastase
Accesso online:https://www.mdpi.com/2076-3271/14/1/106
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