Macrophage Derived Galectin‐3 Promotes Renal Fibrosis and Diabetic Kidney Disease by Enhancing TGFβ1 Signaling

Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease. Renal fibrosis represents the final pathological outcome of most chronic kidney disease, particularly DKD. This study demonstrates elevated l...

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Hlavní autoři:	Yibing Chen, Qian Jiang, Xiaowei Xing, Liu Xu, Qijin Zhao, Qidong Zhang, Jingwen Chen, Chunxiao Ma, Xingfeng Liu, Yinfei Lu, Yanjun Wan, Lijuan Kong, Shaocong Hou, Qian Lu, Bing Cui, Jiankan Guo, Hongdong Huang, Pingping Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2025-09-01
Edice:	Advanced Science
Témata:	DKD galectin‐3 protein degradation renal fibrosis TGFβ1 signaling
On-line přístup:	https://doi.org/10.1002/advs.202504032
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