Targeted Lipid Nanoparticles Encapsulating Dihydroartemisinin and Chloroquine Phosphate for Suppressing the Proliferation and Liver Metastasis of Colorectal Cancer

Antimalarial drugs Dihydroartemisinin (DHA) and chloroquine phosphate (CQ) exhibit evident anti-cancer activity, particularly as combination therapy. DHA and CQ combination therapy has been proved to exhibit higher cytotoxic effect in tumor cells and lower toxicity to normal cells than combination o...

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Autors principals:	Jianqing Peng, Qin Wang, Jia Zhou, Shuli Zhao, Pan Di, Yan Chen, Ling Tao, Qianming Du, Xiangchun Shen, Yi Chen
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-10-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	chloroquine phosphate lipid nanoparticles colorectal cancer liver metastasis ROS dihydroartemisinin
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2021.720777/full
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