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Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo [version 1; referees: 1 approved, 2 approved with reservations]

Background: Micronemal proteins of the thrombospondin-related anonymous protein (TRAP) family are believed to play essential roles during gliding motility and host cell invasion by apicomplexan parasites, and currently represent major vaccine candidates against Plasmodium falciparum, the causative a...

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Autori principali: Simon Gras, Allison Jackson, Stuart Woods, Gurman Pall, Jamie Whitelaw, Jacqueline M. Leung, Gary E. Ward, Craig W. Roberts, Markus Meissner
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wellcome 2017-05-01
Serie:Wellcome Open Research
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Accesso online:https://wellcomeopenresearch.org/articles/2-32/v1
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