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FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients

Abstract Background Epithelial ovarian cancer (EOC) is a spectrum of different diseases, which makes their treatment a challenge. Forkhead box M1 (FOXM1) is an oncogene aberrantly expressed in many solid cancers including serous EOC, but its role in non-serous EOCs remains undefined. We examined FOX...

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Principais autores: Renata A. Tassi, Paola Todeschini, Eric R. Siegel, Stefano Calza, Paolo Cappella, Laura Ardighieri, Moris Cadei, Mattia Bugatti, Chiara Romani, Elisabetta Bandiera, Laura Zanotti, Laura Tassone, Donatella Guarino, Concetta Santonocito, Ettore D. Capoluongo, Luca Beltrame, Eugenio Erba, Sergio Marchini, Maurizio D’Incalci, Carla Donzelli, Alessandro D. Santin, Sergio Pecorelli, Enrico Sartori, Eliana Bignotti, Franco Odicino, Antonella Ravaggi
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-05-01
coleção:Journal of Experimental & Clinical Cancer Research
Assuntos:
Epithelial ovarian cancer
Subtype
Prognosis
Chemoresistance
FOXM1
Cell line
Acesso em linha:http://link.springer.com/article/10.1186/s13046-017-0536-y
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