Cytoskeletal Proteins and Alzheimer’s Disease Pathogenesis: Focusing on the Interplay with Tau Pathology

The aggregation of Tau protein into neurofibrillary tangles (NFTs), a hallmark of Alzheimer’s disease (AD), is associated with cognitive decline. Recent studies have revealed that neuronal cytoskeletal instability drives early AD pathogenesis. The physiological interaction between tau and the microt...

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Autors principals: Gege Jiang, Guanfeng Xie, Xiaoyi Li, Jing Xiong
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2025-06-01
Col·lecció:Biomolecules
Matèries:
Alzheimer’s disease
early stage
neuronal cytoskeleton
tau
post-translationally modified
Accés en línia:https://www.mdpi.com/2218-273X/15/6/831
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