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Transcriptome-wide association study revealed novel causal genes of renal-biopsy proven diabetic nephropathy

Abstract Background While genome-wide association studies (GWAS) have shown that genetic variants are linked to diabetic nephropathy (DN), the precise gene responsible for influencing risk remains largely unidentified, and the issue of missing heritability persists. This study seeks to identify new...

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Principais autores: Zijian Ma, Qing Hou, Ruixiang Yang, Jinsong Shi, Shuyan Kan, Chunxia Zheng, Xiaodong Zhu, Zhihong Liu, Song Jiang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-12-01
Serier:Genome Medicine
Fag:
Diabetic nephropathy
GWAS
TWAS
GYS1
Online adgang:https://doi.org/10.1186/s13073-025-01590-x
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