Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia
Fanconi anemia (FA) is the most prevalent inherited bone marrow failure (BMF) syndrome. Nevertheless, the pathophysiological mechanisms of BMF in FA have not been fully elucidated. Since FA cells are defective in DNA repair, we hypothesized that FA hematopoietic stem and progenitor cells (HSPCs) mig...
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| Автори: | , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Clinical Investigation
2022-08-01
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| Серія: | The Journal of Clinical Investigation |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1172/JCI142842 |
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