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Regulation of Eag1 gating by its intracellular domains

Voltage-gated potassium channels (Kvs) are gated by transmembrane voltage sensors (VS) that move in response to changes in membrane voltage. Kv10.1 or Eag1 also has three intracellular domains: PAS, C-linker, and CNBHD. We demonstrate that the Eag1 intracellular domains are not required for voltage-...

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Bibliografiska uppgifter
Huvudupphov: Jonathan R Whicher, Roderick MacKinnon
Materialtyp: Artigo
Språk:Inglês
Utgiven: eLife Sciences Publications Ltd 2019-09-01
Serie:eLife
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Länkar:https://elifesciences.org/articles/49188
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