Optimizing MATRix as remission induction in PCNSL: de-escalated induction treatment in newly diagnosed primary CNS lymphoma

Abstract Background Primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system (PCNSL) is a rare disorder with an increasing incidence over the past decades. High-level evidence has been reported for the MATRix regimen (high-dose methotrexate (HD-MTX), high-dose AraC (HD-AraC), thio...

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Detalhes bibliográficos

Principais autores:	Julia Wendler, Christopher P. Fox, Elke Valk, Cora Steinheber, Heidi Fricker, Lisa K. Isbell, Simone Neumaier, Jessica Okosun, Florian Scherer, Gabriele Ihorst, Kate Cwynarski, Elisabeth Schorb, Gerald Illerhaus
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-09-01
coleção:	BMC Cancer
Assuntos:	Primary central nervous system lymphoma (PCNSL) High-dose chemotherapy (HCT) Autologous stem cell transplantation (ASCT) Toxicity De-escalation
Acesso em linha:	https://doi.org/10.1186/s12885-022-09723-w
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