Buyang Huanwu Decoction enhances hippocampal-cortical connectivity remodeling via sonic hedgehog signaling to ameliorate memory dysfunction in cerebral ischemic rats

Abstract Background Although Buyang Huanwu Decoction (BHD) has been shown to promote functional recovery of memory following ischemic stroke, the precise mechanisms underlying its therapeutic effects remain incompletely understood. This study aimed to investigate the impact of BHD on hippocampal-cor...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yun Lu, Ziyue Lin, Hanyu Wang, Yuming Zhuang, Jingting Jia, Yuxuan Wang, Le Yang, Manzhong Li, Mingcong Li, Binbin Nie, Rui Zhang, Xu Pan, Jianfeng Lei, Haiyan Zou, Hui Zhao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2025-09-01
Saila:Chinese Medicine
Gaiak:
Buyang Huanwu Decoction
Post-stroke memory dysfunction
Hippocampal-cortical connectivity
Neurogenesis
Sonic hedgehog signaling pathway
Sarrera elektronikoa:https://doi.org/10.1186/s13020-025-01122-0
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