Plasma Aβ42/p-Tau217 ratio and p-Tau217 independently predict CSF-defined Alzheimer’s disease pathology in a Brazilian admixed cohort

IntroductionBlood-based biomarkers offer a promising, minimally invasive approach to Alzheimer’s disease (AD) diagnosis, yet validation in admixed populations remains limited. We investigated whether plasma biomarkers predict CSF-defined AD pathology in a Brazilian cohort.MethodsSeventy-eight older...

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Váldodahkkit:	Liara Rizzi, Isadora Cristina Ribeiro, Marjorie Cristina da Rocha Silva, Ítalo Karmann Aventurato, Luis Eduardo Santos, Ananssa Maíra dos Santos Silva, Thaís Lopes Pinheiro, Gustavo Bruniera Peres Fernandes, Fernanda Guarino De Felice, Marcio L. F. Balthazar
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2026-04-01
Ráidu:	Frontiers in Aging Neuroscience
Fáttát:	Alzheimer’s disease β-amyloid biomarkers diagnosis pathology tau
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fnagi.2026.1773606/full
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