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TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

The faithful segregation of eukaryotic chromosomes in mitosis requires that the genome be duplicated completely prior to anaphase. However, cells with large genomes sometimes fail to complete replication during interphase and instead enter mitosis with regions of incompletely replicated DNA. These r...

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Detalhes bibliográficos
Principais autores: Remi Sonneville, Rahul Bhowmick, Saskia Hoffmann, Niels Mailand, Ian D Hickson, Karim Labib
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2019-09-01
coleção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/48686
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