Activity-dependent CO2 production in the axon triggers opening of Connexin32 in the Schwann cell paranode
Loss of function mutations of Cx32, which is expressed in Schwann cells, cause X-linked Charcot-Marie-Tooth disease, a slowly progressive peripheral neuropathy. Action potential propagation causes Cx32 hemichannels in the Schwann cell paranode to open. As Cx32 hemichannels are directly sensitive to...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
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eLife Sciences Publications Ltd
2026-07-01
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| Reeks: | eLife |
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| Online toegang: | https://elifesciences.org/articles/107085 |
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