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CYP2J2∗7 Genotype Predicts Risk of Chemotherapy-Induced Hematologic Toxicity and Reduced Relative Dose Intensity in Ethiopian Breast Cancer Patients

Chemotherapy-induced hematologic toxicity is the primary reasons of dose reductions and/or delays, low relative dose intensity (RDI), and predicts anticancer response. We investigated the incidence and predictors of chemotherapy-induced hematologic toxicities and reduced RDI in Ethiopian breast canc...

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Principais autores: Jemal Hussien Ahmed, Eyasu Makonnen, Getnet Yimer, Daniel Seifu, Abebe Bekele, Mathewos Assefa, Abraham Aseffa, Rawleigh Howe, Alan Fotoohi, Moustapha Hassan, Eleni Aklillu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019-05-01
Serier:Frontiers in Pharmacology
Fag:
CYP2J2
CYP2C9
chemotherapy
hematologic toxicity
reduced relative dose intensity
breast cancer
Online adgang:https://www.frontiersin.org/article/10.3389/fphar.2019.00481/full
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