MNCLCDA: predicting circRNA-drug sensitivity associations by using mixed neighbourhood information and contrastive learning

Abstract Background circRNAs play an important role in drug resistance and cancer development. Recently, many studies have shown that the expressions of circRNAs in human cells can affect the sensitivity of cells to therapeutic drugs, thus significantly influencing the therapeutic effects of these d...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Guanghui Li, Feifan Zeng, Jiawei Luo, Cheng Liang, Qiu Xiao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-12-01
coleção:	BMC Medical Informatics and Decision Making
Assuntos:	circRNA-drug sensitivity associations Random walk with restart Contrastive learning Graph convolutional network
Acesso em linha:	https://doi.org/10.1186/s12911-023-02384-0
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!