Aberrant KIF26B expression promotes bladder cancer progression through driving NSUN2 nuclear localization

Abstract Abnormal expression of kinesins has been observed in several types of cancer. The present study provided the first evidence that KIF26B could induce RNA m5C modification in bladder cancer (BCa). Detailly, KIF26B interacted with NSUN2 and recruited ubiquitinase STUB1 to promote K63-linked ub...

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Главные авторы:	Jia-Ming Wang, Hai-Yun Xie, Feng-Hao Zhang, Xuan Shu, Jin-Dan Luo, Li-Ping Xie, Jiang-Feng Li
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2025-12-01
Серии:	Journal of Hematology & Oncology
Предметы:	KIF26B NSUN2 Post-translational modification M5C Bladder cancer
Online-ссылка:	https://doi.org/10.1186/s13045-025-01749-4
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