Another power of antibody-drug conjugates: immunomodulatory effect and clinical applications

Antibody-drug conjugates (ADCs) enhance tumour immunogenicity through multidimensional immune modulation beyond targeted cytotoxicity. The immune remodelling of the tumour microenvironment (TME) suggests potential synergistic mechanisms with immune checkpoint inhibitors (ICIs): ICIs amplify antitumo...

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Bibliografski detalji

Glavni autori:	Ruotong Shi, Lin Jia, Zheng Lv, Jiuwei Cui
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2025-08-01
Serija:	Frontiers in Immunology
Teme:	antibody-drug conjugates immune checkpoint inhibitors tumour micro-environment immunoregulation tumour immunology
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1632705/full
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