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SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

Here the authors visualize SARS-CoV-2 infected cells by in situ cryo-electron tomography, delineating the structural organization and conformational changes that occur during virus replication and budding; and provide insight into vRNP architecture and RNA networks in double membrane vesicles.

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Autori principali: Steffen Klein, Mirko Cortese, Sophie L. Winter, Moritz Wachsmuth-Melm, Christopher J. Neufeldt, Berati Cerikan, Megan L. Stanifer, Steeve Boulant, Ralf Bartenschlager, Petr Chlanda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2020-11-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-020-19619-7
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