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Dual role of ACE2 in regulating inflammation triggered by Omicron S1 and other SARS-CoV-2 Spike variants

Since the emergence of SARS-CoV-2 in late 2019, substantial efforts have been made to understand its mechanisms of pathogenicity. Although angiotensin-converting enzyme 2 (ACE2) has been identified as the main receptor for viral entry, the complexity of the host immune response to different Spike pr...

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Principais autores: Annamaria Pedoto, Juan M. Lozano-Gil, María Ocaña-Esparza, Ana M. Conesa-Hernández, Sergio Candel, María L. Cayuela, Victoriano Mulero, Sylwia D. Tyrkalska
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-01-01
coleção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1667880/full
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