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Cysteine Restriction Induces Ferroptosis Depending on the S-adenosylmethionine and Polyamine Biosynthetic Pathways in Hepatic Cancer Cells

Background and Aims: Liver diseases such as hepatocellular carcinoma are known to be affected by nutrition and metabolic activities, but the mechanisms behind them remain unclear. We aimed to reveal the relationship between the concentration of sulfur-containing amino acids and hepatocellular respon...

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Bibliografische Detailangaben
Hauptverfasser: Keisuke Tada, Kazuki Mitsuyama, Hironari Nishizawa, Hiroki Shima, Akihiko Muto, Motoshi Wada, Daisuke Saigusa, Kazuhiko Igarashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2026-01-01
Schriftenreihe:Gastro Hep Advances
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2772572325002043
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