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The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly

Ciliary motility is powered by a suite of highly conserved axoneme-specific dynein motor complexes. In humans, the impairment of these motors through mutation results in the disease primary ciliary dyskinesia (PCD). Studies in Drosophila have helped to validate several PCD genes whose products are r...

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Detalles Bibliográficos
Principais autores: Petra zur Lage, Zhiyan Xi, Jennifer Lennon, Iain Hunter, Wai Kit Chan, Alfonso Bolado Carrancio, Alex von Kriegsheim, Andrew P. Jarman
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2021-10-01
Series:Biology Open
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Acceso en liña:http://bio.biologists.org/content/10/10/bio058812
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