Association between cholesterol and liver injury risk in solid cancer patients treated with PD-1 inhibitors: evidence from two cohort studies

Abstract Background To assess the association between baseline serum lipids and the risk of severe hepatic immune-related adverse events (irAEs) in solid cancer patients treated with PD-1 inhibitors. Methods This retrospective study included a discovery cohort (N = 601) and an independent high-risk...

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Hlavní autoři:	Jing Lei, Yi Wang, Zhiping Jin, Guoyou Qin, Tianshu Liu, Ningping Zhang, Minzhi Lv
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-02-01
Edice:	BMC Cancer
Témata:	Immune checkpoint inhibitor Hepatic immune-related adverse events Lipid metabolism Total cholesterol Low-density lipoprotein cholesterol.
On-line přístup:	https://doi.org/10.1186/s12885-026-15801-0
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