Inhibition of Immune Complex Complement Activation and Neutrophil Extracellular Trap Formation by Peptide Inhibitor of Complement C1

Two major aspects of systemic lupus erythematosus (SLE) pathogenesis that have yet to be targeted therapeutically are immune complex-initiated complement activation and neutrophil extracellular trap (NET) formation by neutrophils. Here, we report in vitro testing of peptide inhibitor of complement C...

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Hlavní autoři:	Pamela S. Hair, Adrianne I. Enos, Neel K. Krishna, Kenji M. Cunnion
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-03-01
Edice:	Frontiers in Immunology
Témata:	immune complex complement system neutrophil extracellular traps NETosis myeloperoxidase peptide inhibitor of complement C1
On-line přístup:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00558/full
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