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Single-cell immune landscape of the central nervous system of mice infected with rabies virus

BackgroundThe fatality rate of virulent rabies virus (RABV) following central nervous system (CNS) invasion is nearly 100%. Infection with the virulent CVS-11 strain is associated with severe neurological symptoms and lethal outcomes, while the attenuated SRV9 strain can be cleared by the host. Alth...

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Principais autores: Xinyue Wang, Xinjie Zhang, Wenwen He, Xianzhu Xia, Pingsen Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-07-01
coleção:Frontiers in Immunology
Assuntos:
central nervous system
immune response
pathogenicity differences
RABV
scRNA-seq
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1850356/full
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