The eIF4EBP-eIF4E axis regulates CD4+ T cell differentiation through modulation of T cell activation and metabolism

Summary: CD4+ T cells are critical for adaptive immunity, differentiating into distinct effector and regulatory subsets. Although the transcriptional programs underlying their differentiation are known, recent research has highlighted the importance of mRNA translation in determining protein abundan...

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Bibliografische gegevens

Hoofdauteurs:	Roman Istomine, Tho-Alfakar Al-Aubodah, Fernando Alvarez, Jacob A. Smith, Carston Wagner, Ciriaco A. Piccirillo
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2023-05-01
Reeks:	iScience
Onderwerpen:	Biological sciences Molecular biology Immunology Proteomics
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2589004223007605
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