Mitochondria and Brain Disease: A Comprehensive Review of Pathological Mechanisms and Therapeutic Opportunities

Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated in the pathogenesis of various brain diseases, including neurodegenerative disorders, stroke, and psychiatric illnesses. T...

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Hauptverfasser:	Vicente Javier Clemente-Suárez, Laura Redondo-Flórez, Ana Isabel Beltrán-Velasco, Domingo Jesús Ramos-Campo, Pedro Belinchón-deMiguel, Ismael Martinez-Guardado, Athanasios A. Dalamitros, Rodrigo Yáñez-Sepúlveda, Alexandra Martín-Rodríguez, José Francisco Tornero-Aguilera
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-09-01
Schriftenreihe:	Biomedicines
Schlagworte:	mitochondria brain disease neurodegenerative disorders mitochondrial DNA mutations oxidative phosphorylation mitochondrial dynamics
Online-Zugang:	https://www.mdpi.com/2227-9059/11/9/2488
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