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The Circadian Transcription Factor CLOCK Modulates Oxidative Stress Resistance via the ACHL–Relish Axis in Drosophila

Abstract Circadian clocks orchestrate temporal regulation of diverse physiological processes, including innate immunity and oxidative stress responses. However, the molecular mechanisms by which core clock components modulate immune tone and redox homeostasis remain elusive. Here, the circadian tran...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Xu Liu, Jiajia Fang, Dawei Cheng, Wei Luan, Yan Lv, Wen Hu, Lei Pan, Yong Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2026-01-01
Schriftenreihe:Advanced Science
Schlagworte:
anti‐microbial peptides
circadian rhythm
CLOCK
oxidative stress
Relish/NF‐κB signaling
RNA‐binding protein ACHL
Online-Zugang:https://doi.org/10.1002/advs.202514388
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