Protection of outbred mice against a vaginal challenge by a Chlamydia trachomatis serovar E recombinant major outer membrane protein vaccine is dependent on phosphate substitution in the adjuvant

Chlamydia trachomatis is the most common bacterial sexually-transmitted pathogen for which there is no vaccine. We previously demonstrated that the degree of phosphate substitution in an aluminum hydroxide adjuvant in a TLR-4-based C. trachomatis serovar E (Ser E) recombinant major outer membrane pr...

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Bibliografische Detailangaben

Hauptverfasser:	Sukumar Pal, Salvador Fernando Ausar, Delia F. Tifrea, Chunmei Cheng, Scott Gallichan, Violette Sanchez, Luis M. de la Maza, Lucian Visan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2020-10-01
Schriftenreihe:	Human Vaccines & Immunotherapeutics
Schlagworte:	chlamydia trachomatis subunit vaccine neutralizing antibody outbreed cd-1 mice aluminum hydroxide adjuvant recombinant major outer membrane protein ifn-γ
Online-Zugang:	http://dx.doi.org/10.1080/21645515.2020.1717183
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