Oncolytic influenza virus infection restores immunocompetence of lung tumor-associated alveolar macrophages

Non-small-cell lung cancer (NSCLC) is the most frequent type of lung cancer and demonstrates high resistance to radiation and chemotherapy. These tumors evade immune system detection by promoting an immunosuppressive tumor microenvironment. Genetic analysis has revealed oncogenic activation of the R...

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Auteurs principaux:	Dörthe Masemann, Katharina Köther, Meike Kuhlencord, Georg Varga, Johannes Roth, Brian Dennis Lichty, Ulf Rüdiger Rapp, Viktor Wixler, Stephan Ludwig
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis Group 2018-05-01
Collection:	OncoImmunology
Sujets:	influenza a viruses lung cancer oncolytic viruses immunotherapy virotherapy immune cell polarization tumor-associated macrophages
Accès en ligne:	http://dx.doi.org/10.1080/2162402X.2017.1423171
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