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Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies

Suitable ex vivo models are required as predictive tools of oromucosal permeability between in vitro characterizations and in vivo studies in order to support the development of novel intraoral formulations. To counter a lack of clinical relevance and observed method heterogenicity, a standardized,...

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Bibliographic Details
Main Authors: Haidara Majid, Andreas Puzik, Tanja Maier, Raphaela Merk, Anke Bartel, Hans-Christian Mueller, Bjoern B. Burckhardt
Format: Artigo
Language:Inglês
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/9/1409
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