Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments
Cell migration through micrometric constraints is limited by low deformability of the nucleus. Here the authors show that in dendritic cells a perinuclear actin network nucleated by Arp2/3 increases nuclear deformation and allows the cells to pass through narrow constrictions, likely by rupturing th...
Na minha lista:
| Principais autores: | , , , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2016-03-01
|
| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/ncomms10997 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|