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A computational investigation of the ventilation structure and maximum rate of metabolism for a physiologically based pharmacokinetic (PBPK) model of inhaled xylene

Physiologically based pharmacokinetic (PBPK) models are systems of ordinary differential equations that estimate internal doses following exposure to toxicants. Most PBPK models use standard equations to describe inhalation and concentrations in blood. This study extends previous work investigating...

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Autori principali: Karen A Yokley, Jaclyn Ashcraft, Nicholas S Luke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bulgarian Academy of Sciences, Institute of Mathematics and Informatics 2019-02-01
Serie:Biomath
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Accesso online:https://biomath.math.bas.bg/biomath/index.php/biomath/article/view/1270
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